Pavone began playing guitar at age 7, with his first professional appearance at age nine. He spent time in rock’n’roll boot camp with the Bill Blue Band. Their album Sing Like Thunder, on Adelphi Records gained notoriety in the Washington D.C., Virginia, and North Carolina areas.

From there Pavone spent the next 9 years with Billy Price and the Keystone Rhythm Band. While with the KRB Pavone recorded two albums. Free at Last on Antenna Records was the band’s first attempt at original compositions. Pavone's music on Win The War was nominated for a W. C. Handy Award.

Rounding out the Cyclones rhythm section is the potent backbeat of Tom Valentine on bass and Frank Sprentz on drums. Valentine’s effortless vocals and Sprentz’s triple threat of original compositions, smooth, polished vocals and forceful percussion take the band to new heights. Valentine and Sprentz, the best-kept secret in Pittsburgh define the rhythm section and provide the solid sound that allows Pavone’s guitar to shine.

With release of their debut CD Twist This, "Oh Babe" was first in spins on WDVE throughout most of 1994. The rockin’ blues sound of Glenn Pavone and the Cyclones is thriving where people come out to drink and dance to live bands. Combining flashy Hendrix solos with blazing licks reminiscent of Stevie Ray Vaughn, the effective steely rock and roll edge of Glenn Pavone and the Cyclones revives the direct form of music that is a perfect release after a work week.